Osteopenia and osteoporosis — both terms for low bone mass, or low bone mineral density — are common complications of ankylosing spondylitis, and both raise the risk of spinal fractures. Show
While lack of physical activity may contribute to low bone mass later in the disease, a study published in July 2015 in the journal RMD Open concluded that inflammation plays a key role in bone loss in ankylosing spondylitis. (9) Other potential complications of ankylosing spondylitis include:
How Ankylosing Spondylitis Causes Aortic RegurgitationSome people with AS develop chronic inflammation at the base of the heart, around the aortic valve, and at the origin of the aorta, the main artery that carries blood away from the heart. Years of chronic inflammation can lead to aortic regurgitation, a condition that occurs when the aortic valve doesn't close properly, causing blood to flow backward. According to the American Heart Association, over time, untreated aortic regurgitation can lead to congestive heart failure, or severe failure of the heart to function properly. A study published in November 2015 in the American Journal of Medicine reported aortic regurgitation may cause symptoms such as dyspnea— uncomfortable or labored breathing — as well as reduced physical capacity and fatigue that might be wrongly interpreted as symptoms related to a person’s ankylosing spondylitis, not to heart problems. (10) In this particular study, aortic regurgitation was found in 18 percent of the participants with ankylosing spondylitis. In addition, aortic regurgitation was associated with both age and severity of ankylosing spondylitis. The researchers suggest that routine care in ankylosing spondylitis include monitoring with both echocardiography and electrocardiography. Once diagnosed, symptomatic aortic regurgitation can be treated with medication or by surgical repair or replacement. Can Ankylosing Spondylitis Cause Costochondritis?Costochondritis is a condition that causes pain and tenderness in the chest. The pain happens in an area called the costosternal joints, where the ribs meet the breastbone. In people with AS, pain in the thoracic spine and around the chest wall is common and is a result of the inflammatory disease. People often have pain in the sternum, costosternal areas, and sternoclavicular joints. Because of the inflammation, there may be inadequate chest expansion. This finding is common enough that it’s included in criteria for ankylosing spondylitis. (11) Ankylosing Spondylitis ProgressionAnkylosing spondylitis is a progressive disease. People with AS may initially have pain in the lower back, sacroiliac joints, or buttocks area that progresses to other areas, including the hips, shoulders, or neck. For some, if the disease goes untreated, the inflammation may cause the spine to fuse. According to the Mayo Clinic, this fusing makes the spine less flexible, resulting in a hunched-forward posture. While knowledge is limited on the triggers of AS progression, researchers believe the following predictors are involved: (12)
Learn the differences between rheumatoid arthritis and ankylosing spondylitis below. Rheumatoid arthritis (RA) and ankylosing spondylitis (AS) are chronic, progressive inflammatory disorders that can impair a patients' physical fitness.
Although both disorders are classified as autoimmune diseases, various distinctions are made to distinguish them. Differences between rheumatoid arthritis and ankylosing spondylitisTable. Differences between rheumatoid arthritis and ankylosing spondylitis
What is rheumatoid arthritis?Rheumatoid arthritis (RA) is an autoimmune illness in which the body's immune system damages the synovium by mistake (the thin membrane that lines the joints).
What are the symptoms of rheumatoid arthritis?Symptoms of RA frequently arise gradually over several weeks. Some cases can move swiftly over days. Symptoms differ from person to person. Symptoms of joint disease include:
Patients with RA experience various more general symptoms, including:
SLIDESHOWWhat Is Rheumatoid Arthritis (RA)? Symptoms, Treatment, Diagnosis See SlideshowWhat the treatment options for rheumatoid arthritis?Treatment options for RA include:
Regardless of the stage, a person is in, their symptoms may persist for a long period. They could go into total remission or flare up and worsen unexpectedly. Health NewsPrevention and outcome of RA
What is ankylosing spondylitis?Ankylosing spondylitis (AS) is a type of arthritis that mostly affects the spine and causes inflammation in the back. The illness affects the shoulders, hips, ribs, heels, and other joints. It is a systemic disease, which means that it affects more than only bones and joints.
QUESTIONThe term arthritis refers to stiffness in the joints. See AnswerWarning signs of AS
What is the treatment of ankylosing spondylitis?AS can be treated conservatively or surgically, depending on the signs and symptoms and the patient's medical state.
The progression of each of these disorders is difficult to predict. Signs and symptoms of AS and rheumatoid arthritis (RA) may recur and then subside. RA and AS, like any other autoimmune or rheumatic disease, are indistinguishable ailments that have disrupted people's lives. The course of an affected individual's life is radically altered because of chronic pain and eventual disability. As a result, supportive care is required to reduce the pain caused by these illnesses. Previously, AS was frequently misdiagnosed as RA. Thanks to advanced laboratory tests and imaging, there are no major diagnostic difficulties in distinguishing between these disorders today. Research suggests that the coexistence of RA with AS is rare. Subscribe to MedicineNet's Arthritis NewsletterBy clicking "Submit," I agree to the MedicineNet Terms and Conditions and Privacy Policy. I also agree to receive emails from MedicineNet and I understand that I may opt out of MedicineNet subscriptions at any time. Medically Reviewed on 3/4/2022 References Image Source: iStock Images Rheumatoid Arthritis and Ankylosing Spondylitis: https://www.ncbi.nlm.nih.gov/books/NBK532288/ Quality of life and work in patients with rheumatoid arthritis and ankylosing spondylitis of working age: https://ard.bmj.com/content/62/12/1178 Rheumatoid Arthritis (RA): https://www.cdc.gov/arthritis/basics/rheumatoid-arthritis.html Overview of Ankylosing Spondylitis: (https://spondylitis.org/about-spondylitis/types-of-spondylitis/ankylosing-spondylitis/) COEXISTENCE OF ANKYLOSING SPONDYLITIS AND RHEUMATOID ARTHRITISS: https://onlinelibrary.wiley.com/doi/epdf/10.1002/art.1780190120 What type of arthritis is ankylosing spondylitis?Ankylosing spondylitis (AS) is a type of inflammatory arthritis that affects the spine and the sacroiliac joints that attach the pelvis to the base of the spine. 'Ankylosing' means fusing and 'spondylitis' means inflammation of the spine.
What's the difference between rheumatoid arthritis and ankylosing spondylitis?The type and localisation of arthritis is peripheral polyarthritis in RA, especially with involvement of hands and feet, whereas in AS the arthritis is mainly localized in the spine and sacroiliac joints with an oligoarthritis of the larger joints (hips, knees, shoulders).
What is ankylosing spondylitis classified AS?Ankylosing spondylitis is a type of arthritis that causes lower back pain. Symptoms, including hip pain and a stiff back that may come and go. Over time, vertebrae in the spinal column may fuse and become rigid (ankylosis).
What is the difference between rheumatoid arthritis and spondyloarthritis?RA tends to affect the peripheral joints (small joints of the hands and feet) and dose not affect the spine. Spondyloarthritis tends to affect the spine with little or no effect on the peripheral joints. The pathogeneic basis for the disease, and associated genetic and autoantibody features are also different.
|