How long after oral herpes outbreak is it still contagious

Infectious Diseases Herpes: HSV-1 and HSV-2 Sexually Transmitted Diseases

What You Need to Know

  • Fifty percent to 80 percent of U.S. adults have oral herpes.
  • Oral herpes can be spread through intimate contact with someone who is infected.
  • Oral herpes can be difficult to diagnose. Often confused with many other infections, it can only be confirmed with a virus culture called PCR, blood test or biopsy. PCR is the preferred test for diagnosing herpes infections.
  • The best treatment for oral herpes is antiviral oral medication. Symptomatic treatment may include antiviral ointment, over-the-counter topical anesthetics or over-the-counter anti-inflammatory agents.

Whether you call it a cold sore or a fever blister, oral herpes is a common infection of the mouth area that is caused by herpes simplex virus type 1 (HSV-1). Fifty percent to 80 percent of U.S. adults have oral herpes. According to the National Institutes of Health, about 90 percent of adults have been exposed to the virus by age 50.

Once infected, a person will have herpes simplex virus for the rest of his or her life. When inactive, the virus lies dormant in a group of nerve cells. While some people never develop any symptoms from the virus, others will have periodic outbreaks of infections.

Causes of Oral Herpes

Oral herpesis spread most commonly from individuals with an active outbreak or sore. You can catch oral herpes by engaging in intimate or personal contact (e.g., kissing or oral sex) with someone who is infected.

Prevention of Oral Herpes

Since oral herpes is spread through direct, physical contact, the best method of prevention is to avoid physical contact with a person’s herpes sores when they are having an outbreak.

Oral Herpes Symptoms

The initial (primary) infection of oral herpes is usually the worst. It may cause severe, flu-like symptoms, including swollen lymph nodes and headache. However, some people have no symptoms at all. During the initial infection, sores can occur on and around the lips and throughout the mouth. 

Recurring infections tend to be much milder, and the sores usually erupt on the edges of the lips. Some people never have any additional outbreaks beyond the initial infection. The following are the most common signs and symptoms of a recurring oral herpes simplex virus infection.

  • Initial redness, swelling, heat/pain or itching may develop in the area where the infection will erupt.

  • Painful, fluid-filled blisters may appear on the lips or under the nose. The blisters and fluid are highly contagious.

  • The blisters will leak fluid and become sores.

  • After about four to six days, the sores will start to crust over and heal.

The signs and symptoms of an oral herpes outbreak may look like other conditions or medical problems. Always consult your health care provider for an accurate diagnosis.

Diagnosing Oral Herpes

Since oral herpes can be confused with many other infections, including allergic reactions, a virus culture (PCR), blood test or biopsy are the only ways to confirm your diagnosis. However, your health care provider may also diagnose your condition based on the location and appearance of the blisters.

Recurrence of Oral Herpes

Although the specific triggers that cause oral herpes to recur are unclear, several factors may play a role. These include:

  • A recent fever

  • Emotional stress

  • Menstruation

  • Physical injury 

  • Prolonged or intense exposure to sunlight

  • Surgery

While recurrent outbreaks are more common in the first year after the initial episode, they tend to lessen as the body builds antibodies to the virus.

Oral Herpes Treatment Options

Your health care provider will recommend treatment options based on your:

  • Age

  • Expected outcome

  • Overall health and medical history

  • Personal preference

  • Tolerance for specific medicines, procedures or therapies

Your specific treatment plan may involve:

  • Keeping the infected area clean and dry

  • Taking antiviral oral medications, such as acyclovir, famciclovir and valacyclovir (these medications are traditionally the most effective)

  • Applying antiviral topical ointments, such as acyclovir and penciclovir

  • Using over-the-counter topical anesthetics or anti-inflammatory agents to alleviate symptoms

Herpes Simplex Virus (HSV) Mouth Infection

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What is a herpes simplex virus (HSV) mouth infection? 

Some people call it a cold sore, others a fever blister. Herpes simplex virus is the cause of this annoying and often painful chronic condition.

The herpes sores (lesions) typically last a week to 10 days. They most often occur on the lips, tongue, roof of the mouth, or the gums. The sores occur first as fluid-filled blisters that burst (rupture) after a day or 2. The sores will ooze fluid that has the virus. After a few days, the sores will form crusts or scabs. The virus is highly contagious and can be spread by skin-to-skin contact such as kissing.

What causes an HSV mouth infection?

The virus is spread by skin-to-skin contact with someone who carries the virus. Most people with oral herpes were infected during childhood or as young adults from nonsexual contact with infected saliva. It can be passed by kissing, touching the infected person's skin, or sharing infected objects such as lip balm, silverware, or razors.

The 2 most common forms of the virus are:

  • Herpes simplex virus type 1 (HSV-1). HSV-1 is most often linked to infections of the mouth.
  • Herpes simplex virus type 2 (HSV-2). This type is most often linked to genital herpes infections.

Both types of HSV can infect both the mouth and the genitals.

Once infected, a person will have the herpes simplex virus for the rest of their life. When the virus is not active, it is dormant in a group of nerve cells. Some people never have any symptoms from the virus while others have periodic outbreaks of infections.

It is not clear what triggers the virus to return. But the risk factors below may play a role:

  • Long or intense exposure to sunlight
  • A recent fever
  • Emotional stress
  • Menstruation
  • Surgery
  • Physical injury

Recurrent outbreaks are more common in the first year after the initial episode. After that, the outbreaks diminish in frequency and severity as the body builds antibodies to the virus.

What are the symptoms of an HSV mouth infection?

The initial (primary) infection of the oral herpes simplex virus is often the worst. It may cause severe, flu-like symptoms, swollen lymph nodes, and headache. But some people have no symptoms at all. In the initial infection, sores can occur on and around the lips and all over the mouth.

Recurring infections tend to be much milder, and the sores often erupt in the edges of the lips. Some people never have any more outbreaks beyond the initial infection. These are the most common symptoms of a recurring oral HSV infection:

  • Initial redness, swelling, heat, and pain, or itching in the area where the infection will erupt.
  • Painful, fluid-filled blisters may appear on the lips or under the nose. These blisters, and the fluid they contain, are highly contagious.
  • The blisters leak fluids and become sores.
  • After about 4 to 6 days, the sores start to crust over and heal.

The symptoms of an oral HSV outbreak may look like other conditions or health problems. Always see your healthcare provider for a diagnosis.

How is an HSV mouth infection diagnosed?

Herpes simplex virus may be difficult to diagnose because it may be confused with many other infections, such as allergic reactions. HSV can be confirmed only with a virus culture, blood test, or biopsy. A healthcare provider can often diagnose it based on where the blisters are and how they look. 

How is an HSV mouth infection treated?

Treatment will depend on your symptoms, age, and general health. It will also depend on how severe the condition is.

Treatment may include:

  • Keeping the infected area clean and dry
  • Antibiotic treatment for any secondary bacterial infections
  • Topical antiviral creams
  • Oral antiviral medicines

What can I do to prevent an HSV mouth infection?

These tips can help you prevent an oral HSV infection:

  • Don’t have direct contact with someone with herpes sores. According to the CDC, genital herpes (HSV-2) can be contagious without any symptoms.
  • Don’t share silverware, glasses, straws, or other items with someone who has oral herpes.
  • Wash bedding and towels in boiling hot water after each use.
  • Don’t have oral sex if you or your partner have oral herpes (HSV-1). HSV-1 can be spread to the genitals, especially if you have oral blisters.
  • To prevent a possible recurrence, use a sunblock that contains zinc oxide on your lips.

Key points about an HSV mouth infection

  • A cold sore or fever blister is caused by the herpes simplex virus.
  • The virus is highly contagious and can be spread by skin-to-skin contact such as kissing.
  • Once infected, a person will have the herpes simplex virus for the rest of their life.
  • Herpes sores typically last a week to 10 days. They most often occur on the lips, tongue, roof of the mouth, or the gums.

Next steps

Tips to help you get the most from a visit to your healthcare provider:

  • Know the reason for your visit and what you want to happen.
  • Before your visit, write down questions you want answered.
  • Bring someone with you to help you ask questions and remember what your provider tells you.
  • At the visit, write down the name of a new diagnosis and any new medicines, treatments, or tests. Also write down any new instructions your provider gives you.
  • Know why a new medicine or treatment is prescribed and how it will help you. Also know what the side effects are.
  • Ask if your condition can be treated in other ways.
  • Know why a test or procedure is recommended and what the results could mean.
  • Know what to expect if you do not take the medicine or have the test or procedure.
  • If you have a follow-up appointment, write down the date, time, and purpose for that visit.
  • Know how you can contact your provider if you have questions.

Medical Reviewer: Michael Kapner MD

Medical Reviewer: Rita Sather RN

Medical Reviewer: Stacey Wojcik MBA BSN RN

© 2000-2022 The StayWell Company, LLC. All rights reserved. This information is not intended as a substitute for professional medical care. Always follow your healthcare professional's instructions.

Not what you're looking for?

How long after oral herpes outbreak are you contagious?

How long are cold sores contagious for? Cold sores, caused by a type of virus called herpes simplex type 1, are contagious until they completely go away, which usually takes about two weeks. Cold sores are the most contagious when fluid seeps out of the sores.

Is oral herpes permanently contagious?

Once you contract HSV-1, you have the virus for life. While you'll always be able to spread the virus, you're most contagious when you have an active cold sore.

How long after cold sore can you kiss?

In general, it's best to wait for three to four days after the cold sore scab disappears before you kiss someone or engage in oral sex. This is because the herpes virus can continue shedding in the late stages of a cold sore healing, even if there's no viral fluid present.

Is oral herpes still contagious after scabbing?

Cold sores, aka fever blisters, are caused by the herpes simplex virus (HSV) — not by colds or fevers. But like colds, they are very contagious. You can spread HSV at any point from the first warning tingle up until the cold sore scab has completely disappeared.