While cholesterol level monitoring is especially important for people with familial hypercholesterolemia, or FH, everyone should know what state their cholesterol is in. Cholesterol levels tell you a lot about the health of your cardiovascular system, since excess cholesterol can lead to the kind of plaque buildup that may eventually trigger a major cardiac event. However, if you get your cholesterol tested, it’s important to understand exactly what you’re looking at, because not all cholesterol is bad for you. Some cholesterol is actually a sign of positive health. Show
Getting Your Cholesterol Levels Tested First, you need to know what testing for cholesterol level entails. The American Heart Association suggests that all adults age 20 or older should have what’s called a fasting lipoprotein profile every five years. This is a blood test that is done after a 9-12 hour fast without any food, liquids, or pills, producing four different measurements: total cholesterol, LDL cholesterol (the bad kind), HDL cholesterol (the good kind), and triglycerides. The test results will be reported as milligrams per deciliter of blood. Understanding Your Cholesterol Test Results While your doctor can help you take into account the risk factors that may shift these general guidelines slightly for your individual case, this is the basic rubric for what your cholesterol test results mean.
Cholesterol Numbers in Individuals with FH LDL-C levels are the most important potential sign of FH that can be derived from a cholesterol test. Adults with LDL-C levels of 190 mg/dL or above and children with LDL scores of 160 mg/dL or above should consider further testing for FH, especially if they have a family history of heart disease, stroke or high cholesterol. For more information about FH or to find out how you can get involved, contact the Family Heart Foundation today. Ah, cholesterol and triglycerides. We hear about them all the time. Even foods that might seem good for you on the surface, like fruit-filled yogurt or bran muffins, can contribute to abnormal levels if they contain too much saturated fat or refined sugar, says Erin Michos, M.D., associate director of preventive cardiology at the Ciccarone Center for the Prevention of Heart Disease. What’s more, many women are at risk for high cholesterol and don’t realize it. “Approximately 45 percent of women over the age of 20 have a total cholesterol of 200 mg/dl and above, which is considered elevated — but a survey by the American Heart Association found that 76 percent of women say they don’t even know what their cholesterol values are,” Michos says. Scarier still: Triglycerides, a type of blood fat typically measured alongside cholesterol, are even more risky in women compared with men. This is a problem because women’s cholesterol levels can fluctuate quite a bit after menopause and tend to increase with age, putting us at greater risk of heart disease and stroke. Knowing your cholesterol numbers and how to control them is a big step toward staying healthy. Understanding the Highs and Lows of CholesterolYou know that too much is dangerous. But what is cholesterol, anyway? Where does it come from? And is it all bad? Cholesterol is a waxy substance that is found in every cell in the body. It’s either made by the body or absorbed from food. Your body needs cholesterol to make important steroid hormones such as estrogen, progesterone and vitamin D. It’s also used to make bile acids in the liver; these absorb fat during digestion. So some cholesterol is necessary — but bad cholesterol is something you can do without. Excess bad cholesterol in the bloodstream can deposit into the body’s arteries. These deposits are called plaques and result in atherosclerosis, or hardening of the arteries. This is the major cause of heart attacks, strokes and other vascular problems. Your total cholesterol level is a measure of the total amount of cholesterol circulating in your bloodstream, which includes several components:
So bits of this stuff circulate through your system, and here’s what happens: The bad parts – the LDL particles – like to stick to the lining of your arteries, like soap scum in pipes. As it sticks there, it generates an inflammatory response and your body starts converting it into plaque. Plaque in your blood vessels makes them stiffer and narrower, restricting blood flow to vital organs such as your brain and heart muscle, leading to high blood pressure. Additionally, chunks can break off and cause a heart attack or a stroke. And guess what? This buildup can start as early as your 20s. What to Know About TriglyceridesIn addition to cholesterol, you might hear about your triglycerides, another kind of fat found in the bloodstream. Women should pay particular attention to this. “A high level of triglycerides seems to predict an even greater risk for heart disease in women compared with men,” says Michos. When you take in more calories than you need, your body converts the extra calories into triglycerides, which are then stored in fat cells. Triglycerides are used by the body for energy, but people with excess triglycerides have higher risk of medical problems, including cardiovascular disease. Drinking a lot of alcohol and eating foods containing simple carbohydrates (sugary and starchy foods), saturated fats and trans fats contributes to high triglycerides. High levels may also be caused by health conditions such as diabetes, an underactive thyroid, obesity, polycystic ovary syndrome or kidney disease. Triglycerides also circulate in the bloodstream on particles that may contribute to plaque formation. Many people with high triglycerides have other risk factors for atherosclerosis, including high LDL levels or low HDL levels, or abnormal blood sugar (glucose) levels. Genetic studies have also shown some association between triglycerides and cardiovascular disease. Cholesterol is a natural component in everyone’s blood. However, when you have too much of this fatty substance, it’s considered hyperlipidemia, hypercholesterolemia or high blood cholesterol—a major risk factor for heart attack, heart disease and stroke. About 71 million Americans have high cholesterol. Learn more What’s your cholesterol level, anyway?A standard lipid blood test usually measures the concentration of total cholesterol, HDL cholesterol, and triglycerides levels. The LDL-cholesterol level is typically estimated from these numbers using a well-established formula that has been more recently revised and improved by researchers at Johns Hopkins. So what are your target numbers? According to Michos, an ideal LDL cholesterol level should be less than 70 mg/dl, and a woman’s HDL cholesterol level ideally should be close to 50 mg/dl. Triglycerides should be less than 150 mg/dl. As Michos notes, total cholesterol levels well below 200 mg/dl are best. Why Cholesterol Affects Women DifferentlyIn general, women have higher levels of HDL cholesterol than men because the female sex hormone estrogen seems to boost this good cholesterol. But, like so much else, everything changes at menopause. At this point, many women experience a change in their cholesterol levels — total and LDL cholesterol rise and HDL cholesterol falls. This is why women who had favorable cholesterol values during their childbearing years might end up with elevated cholesterol later in life. Of course, genetics and lifestyle factors can play big roles, too. How to Lower Your CholesterolIf you’ve been told that you have high cholesterol — or you just want to prevent it — what can you do? There are several ways to manage it, including: Medication: Depending on your overall cardiovascular disease risk, you might be treated with a cholesterol-lowering medication, such as a statin. The decision to use a statin is based on a woman’s overall risk for heart attack and stroke including all these factors and the LDL cholesterol value. If you already have vascular disease or evidence of atherosclerosis, or if you are at high risk for cardiovascular disease, a statin for prevention is strongly recommended because this treats the plaque in the arteries, and lowers LDL cholesterol, Michos says. Diet and lifestyle: “Diet and lifestyle are very important to help maintain healthy cholesterol levels. Even for women who are recommended to take cholesterol-lowering medications, a healthy lifestyle helps these drugs work better,” says Michos. Here’s how to maintain a lifestyle that promotes healthy cholesterol levels:
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While nobody wants to have high cholesterol, there are plenty of ways to keep it in check. “With regular checkups and attention to what you eat, it’s possible to manage your cholesterol and blood fats to keep your heart healthy,” says Michos. One of the best things you can do to protect and improve your health is to stay informed. Your Health is a FREE e-newsletter that serves as your smart, simple connection to the world-class expertise of Johns Hopkins. Sign Up If you have a new or existing heart problem, it's vital to see a doctor. Our heart health checklist can help you determine when to seek care. |